The management of prostate cancer has changed significantly in recent years, particularly the use of imaging.

A patient presents with soreness and weakness of both hands, which he developed following the use of a walking frame.

Patients prescribed high doses of opioids need to be managed appropriately to reduce risks of morbidity and mortality.

A man aged 53 years presents with a 1–2-month history of a rapidly increasing skin growth on his right medial ankle.

For patients already undergoing treatment, replacing interfering medications results in fewer false positives and false negatives.

The host immune system appears to have a fundamental role in almost all human disease.

Given the current global context, heightened vigilance is essential for early detection and management of any imported measles cases.

Management provides a key contribution to lowering individual risk of tuberculosis and reducing Australian tuberculosis incidence towards elimination.

This clinical challenge is based on this month’s Focus articles. To complete this activity, go to the RACGP website.

People who are immunosuppressed may benefit from deferring vaccination.

Immunosenescence, altered pharmacokinetics and the presence of multiple comorbidities can all affect response to immunosuppressants.

The host immune system appears to have a fundamental role in almost all human disease.

Readers express their opinions on published articles and topics of interest.

Better defining, integrating and supporting general practitioner roles in disaster systems is likely to improve disaster healthcare.

Pharmaceutical industry interactions with professional medical associations have come under scrutiny, yet industry ties among the leadership of these associations are often overlooked.