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GPs asked to limit antibiotic scripts due to ‘unprecedented’ shortage


Chelsea Heaney


21/06/2024 4:52:05 PM

A rise in pneumonia and whooping cough cases is exacerbating the situation, with azithromycin and clarithromycin particularly affected.

Antibiotic and empty jar
Several antibiotic treatments are in short supply in Australia.

NSW Health has requested that GPs limit prescriptions of two antibiotics amid a national shortage and rising rates of pneumonia, whooping cough and respiratory viruses in the state.
 
The request, sent out to GPs on 18 June, states that antibiotic oral liquids, including azithromycin and clarithromycin, may be in short supply due to increased demand.
 
‘Carefully consider the need for antibiotic treatment and if prescribing an antibiotic, consider current availability by consulting your local pharmacy,’ it reads.
 
The shortage, which is nationwide, is particularly acute in NSW due to the current rise in pneumoniae and pertussis infections.
 
Hurstville GP Dr Mariam Chaalan told Nine Newspapers she drove for four hours to find a pharmacy stocked with azithromycin for her sick son.
 
‘I knew he just wouldn’t be able to do a two-a-day dose antibiotic regime for seven days,’ she said.
 
Dr James Best, Chair of RACGP Specific Interests Child and Young Person’s Health, told newsGP generally GPs are ‘on the money’ when prescribing but there may a lack of awareness in the limited role of antibiotics for mild-to-moderate cases.
 
‘I think that was useful for us,’ he said.
 
‘Because we do really need to be hanging on to the antibiotics for the more severe cases.’
 
However, Dr Best has spoken out against an apparent move from Pfizer to limit its remaining stock of azithromycin oral liquid to hospitals only, saying it is ‘not appropriate’ and should only happen when it is ‘absolutely necessary from a supplier point of view.’

‘In general practice, we are seeking keep a child out of hospital,’ he said.
 
RACGP NSW&ACT Chair Dr Rebekah Hoffman told newsGP the shortage is leaving GPs with ‘a lot more legwork’.
 
‘This increases our workload significantly,’ she said.
 
‘It means that we have to call our pharmacists and ask what have you got in stock? What don’t you have in stock? What am I able to prescribe for my patients?
 
‘Sometimes that means calling one pharmacist or calling two or three or four pharmacists until we’re able to find one.’
 
But there is more urgency, Dr Hoffman says, when vulnerable people are unable to access the right medication.
 
‘For many patients they do need a course of antibiotics, especially when we’re talking about pregnant women and newborns,’ she said.
 
‘If they’re not able to access appropriate antibiotics we’re going to see it spread to more people at higher risk.’
 
In its letter to GPs, NSW Health ran through several treatment options, stating that ‘antibiotics have limited efficacy in most mild-moderate cases of confirmed or suspected Mycoplasma pneumoniae infection’.
 
It also notes that an international alternative, azithromycin (Zydus) 200 mg/5 mL powder for oral suspension, remains available.
 
To help manage the shortage, Dr Hoffman has been incorporating more testing into her practice, using swab tests to provide certainty about the infection.
 
‘When our patients come to see us, we are doing a swab test, like the same as we do with COVID, and adding that into our consults,’ she said.
 
‘They’ve got really fast turnaround times for those tests at the moment and usually they’re back within 24 hours.
 
‘If they’ve got RSV or another virus, we can reassure them that they don’t need antibiotics and that they will get better without them.’
 
With the shortage not limited to just azithromycin and clarithromycin, Dr Best says he is growing increasingly concerned about other antibiotics, such as Bicillin L-A, being unavailable in Australia.
 
‘These antibodies can be lifesaving at times, it can stop progression to severe disease,’ he said.
 
‘It’s a very large concern. If we don’t have the tools that we normally have available that can be very, very dangerous.’
 
A NSW Health spokesperson told newsGP the supply disruption is being addressed at a ‘national level’ by the Therapeutic Goods Administration.
 
‘Suppliers are working to expedite future shipments, with normal supply expected to resume over the coming months,’ they said.
 
Dr Hoffman is hopeful normal services returns even sooner.
 
‘It gets really tricky when we have antibiotic shortages,’ she said.
 
‘Often they’re unprecedented antibiotic shortages, we don’t know about them and we can’t expect them.’
 
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Dr Irandani Anandi Ranasinghe-Markus   22/06/2024 8:27:33 AM

Controlling antibiotics which help GPs do their job in primary health care to avoid overloading an already stretched tertiary care system is another perfect example of undermining the role of primary health care in this country.
I have, like several of my colleagues diligently swabbed children who present with moderate to severe respiratory symptoms, managed them symptomatically until the swab results are through (quick turnaround in most cases) and prescribed Azithromycin for where it would be expected to keep that child out of hospital. Much time is spent calling around to source the antibiotic or discussing alternatives with microbiologists . By exerting controls that prevent GPs from doing this, emergencies departments will be flooded.
The smart solution would be to investigate this shortage and fix it! Not make it look like GPs are incompetent!


Dr James Courts   22/06/2024 8:29:08 AM

Currently in QLD swabs are taking up to 5 days, also seeing many infections with mycoplasma + other, so the simplistic approach you describe is not feasible.

Instead of encouraging pharmacists to be diagnosticians maybe ensuring adequate drug supplies and sorting alternatives might be a better scope of practice.


DR M   22/06/2024 9:37:28 AM

Hang on a minute, we have enough to do without having to chase around looking for availability. That is for the pharmacist to do, We write the scripts , they provide the medication, if they don't have it they search for supply, If none available anywhere then the pharmacist calls the prescriber. That is their job.
It makes my blood boil when the patient comes back to me with " the chemist said this medication is not available, go back to your doctor",


Dr Horst Paul Herb   22/06/2024 12:56:27 PM

the issue of inappropriate antibiotic prescribing set aside, I get the feeling that "unprecedented medication shortages" are becoming the rule rather than the exception. Recently we couldn't even get Benzathine Penicillin any more, Semaglutide has been iin crisis mode for quite a while now, what next? Methinks a health system simply cannot afford to rely on private industry alone for secure supplies of essential drugs. The "market" only ever seems to work for the interests of the suppliers in times of crisis.


A.Prof Christopher David Hogan   22/06/2024 6:11:29 PM

Of dear, blame the GP when the system fails
Do not provide GPs with adequate resources
Do nothing to address the abysmally poor level of community Health Literacy which leads to patients making extremely inappropriate demands on GP


Frustrated GP   25/06/2024 3:38:51 PM

This is classic blame shifting from the government.
There are objectively more cases of, for example, Mycoplasma pneumoniae and pertussis circulating at present, so there will objectively be more need for antibiotics.
This is yet another failure of successive governments to ensure Australia has adequate supply of vital medicines.
If only Australia did something innovative like manufacture medicines?!