Advertising


News

Wegovy launches in Australia


Chelsea Heaney


2/08/2024 3:40:39 PM

The manufacturer assured GPs supply planning has been its priority amid critical Ozempic shortages, but concerns remain over Wegovy’s availability.

A tape measure lies next to a semaglutide device.
The weight loss targeted drug Wegovy has a significantly greater cost to customers than Ozempic.

A new semaglutide drug specifically targeted for weight loss is hitting the Australian market next week for the first time, with manufacturer Novo Nordisk to launch Wegovy on 5 August.
 
The medication is indicated for chronic weight management for those living with obesity or are overweight with at least one weight-related comorbidity, such as high blood pressure, type 2 diabetes, or high cholesterol.
 
While welcomed, its launch has been met with concern and some scepticism from GPs amid the worldwide critical shortages of Ozempic.
 
The Therapeutic Goods Administration (TGA) last year issued firm advice to GPs to not initiate new patients on Ozempic due to its short supply, and that is showing no signs of easing any time soon.
 
Chair of RACGP Specific Interests – Obesity Management and dietitian Dr Terri-Lynne South told newsGP it was interesting to see the product enter the market in a time of shortage, but the high price point of Wegovy would likely keep demand low.
 
‘My understanding is that, of course, the company is trying to increase its factories and manufacturing of semaglutide,’ she said.
 
‘I think it’s interesting that there is still supply issues, but they’re introducing a new version of it.
 
‘But the drug company reps that I’ve spoken to have reassured me that they don’t feel that there’s going to be a supply problem, and that’s probably because of the price.’
 
Novo Nordisk Corporate Vice President and General Manager Cem Ozenc told newsGP significant work has been done to prevent a shortage.

‘The unexpected and overwhelming interest from the public in Ozempic took us by surprise and therefore supply planning for Wegovy has been a priority,’ he said.
 
‘We have worked hard for two years to ensure a stable supply of Wegovy 2.4mg in Australia.
 
‘Novo Nordisk has two products containing semaglutide; Ozempic indicated for type 2 diabetes and Wegovy indicated for chronic weight management.
 
‘It is important that patients are prescribed and use the approved treatment for the right disease to ensure they achieve the best medical outcomes to improve their condition and health.’
 
But that treatment comes with a price tag.
 
Novo Nordisk told newsGP the 2.4 mg dosage of Wegovy, which it says is the ‘recommended dose for the most effective results for weight management’, costs $460 per dose.
 
The 0.25 mg, 0.75 mg, and 1.0 mg cost $260, and the 1.7 mg is $380, with each dose lasting one month.
 
Chair of RACGP Specific Interests – Diabetes Dr Gary Deed welcomed the announcement but said he had some concern.
 
‘Finally, a chance to allow people with overweight or obesity that suit the new medication to have availability of supply,’ he told newsGP.
 
‘What remains, however, is why there appears to be ample supply for Wegovy, the same ingredient, but the Ozempic supply remains compromised until further notice?
 
‘Also, will Novo Nordisk allow there to be a pricing parity between these products (privately scripted) so as not to further hinder people with chronic weight management issues getting the support they need?’
 
Dr South said it was good to have another treatment option for the complex chronic condition of obesity but that it raised questions for both obesity and diabetes patients.
 
‘How do you choose between patient population groups for priority access?’ she said.
 
Dr South said GPs will continue to have valid concerns about initiating this new drug considering the ongoing nature of treatment and access issues.
 
‘I think it definitely needs to be taken into consideration that someone is starting this medication for a chronic complex condition, and therefore they’re going to need lifelong management,’ she said.
 
‘I think a lot of patients don’t necessarily realise that an intervention, from a weight control point of view, isn’t a short-term thing, that it ultimately is for the long term and potentially the rest of their life.
 
‘So that would be where GPs should have some reasonable discussions with their patients about informed consent that also includes access, cost and expectations about weight loss as well as length of treatment.’
 
Log in below to join the conversation.



obesity PBS Pharmaceutical Benefits Scheme semaglutide Wegovy weight loss


newsGP weekly poll If you still use the phone line for PBS authorities, how long do you spend waiting on average?
 
1%
 
20%
 
48%
 
25%
 
4%
Related





newsGP weekly poll If you still use the phone line for PBS authorities, how long do you spend waiting on average?

Advertising

Advertising


Login to comment

Dr Robert Charles P Hills   2/08/2024 11:25:02 PM

I'm astounded!
Dr South makes very valid points about differing availability of the two brands of Semaglutide.
But how can the company justify the huge financial discrimination against patients who need this drug to treat their obesity? And how can the TGA justify supporting this?
I am astounded by what looks to me like corporate-level fat shaming.


Dr Anne Saunders   3/08/2024 4:17:33 PM

I am very concerned about the sophistry in evidence here. Ozempic and Wegovy are brand names for semaglutide. The pens are the same the dosing increase is the same although extends to higher doses with wegovy. But the price point is almost double for wegovy in comparison to ozempic.

Somehow by changing the disease we are trying to manage, the exact same drug costs more???? This seems to be punitive and reinforcing of the stigma overweight people experience widely. There will be many economic arguments about what the market will bear, but this is literally the case of a name change resulting in higher costs.

One of the pillars of medical ethics is justice and I do not see how this is fair at all.


Dr sceptical   4/08/2024 9:22:39 AM

Is it only me or there is any one else having objection for the exact same medicine same device same dose 0.25mg and 1 mg Novo Nordisk is allowed to charge double the price because it is marketed for obesity. There is also an emphasis that the right drug should be used for the right indication ozempic for diabetes and Wegovy particularly 0.25mg and 1 mg for weight loss at twice the price. Can someone please explain the actual difference between the two beside the label.


Dr Robert Charles P Hills   5/08/2024 11:34:15 AM

To my colleagues suggesting that the price for Wegovy is double that for Ozempic, I suggest you look a little closer.

Patients using Ozempic on a private script pay around $150-$170 for either the 2mg/1.5ml or 4mg/3ml pen. On the starting dose of 0.25mg a small pen contains up to 8 doses and a large pen up to 16 doses, so this works out to ~$10-$20 per dose.

It's a bit unclear to me whether the indicated $260-460 price range for Wegovy is for single dose pens as indicated in this article, or for 4-dose "FlexTouch" pens mentioned in the Product Information document submitted to the Australian Register of Therapeutic Goods (ARTG - https://www.ebs.tga.gov.au/ebs/picmi/picmirepository.nsf/pdf?OpenAgent=&id=CP-2022-PI-01930-1&d=20240805172310101)
If we take an optimistic view and assume our patient needing a 0.25mg weekly dose of Semaglutide gets a 4-dose pen of Wegovy for $260, this works out at $65 per dose, or 3-6 times what they'd pay for Ozempic.


Dr Lee   5/08/2024 12:24:15 PM

How corrupted RACGP has became by putting a non-essential private scripted medication as headline GP news to clickbait us! I expect my union to advocate more on a sugar tax or ban of ultra processed food/seed oil to tackle the problem of obesity


Dr Astonished   5/08/2024 2:09:49 PM

Having a much needed holiday in SE Asia.
I can count the number of obese people I've seen today on one hand.

And here we have educated folk crying "justice" over the availability of a high priced luxury. This is what our economy and way of life have produced.

It may shock people to understand that Novo Nordisk doesn't owe anyone cheap semaglutide any more than Samsung owes you a cheap TV.


Dr Julian Hadden Fidge   5/08/2024 3:08:40 PM

My colleagues are correct - but the first rule of business is to charge as much as the market will bear, and it is this business model that brings so many good drugs to market.
And the price discrepancy goes to prove how good the PBS is for Australians. Shouldn't the PBS be listing these drugs, too?
Over time, I expect the developing market to reduce obesity treatment prices, and definitely after the patents for these innovators expire.
Or if the PBS decides to list these medications...
J


Dr RA   17/08/2024 9:00:33 AM

Whilst this debate about ozempic and wegovy drags on for weight management, has anyone but myself noticed how difficult it is to get ozempic on PBS authority for diabetics now? Forget new scripts even patients who have been on it often don’t meet the criteriae , and either have to pay full private script price or discontinue it. Another example of government hypocrisy in taking care of people’s healthcare needs. I can’t understand why they could not trim 5 billion off the bloated NDIS budget and channel that into medicare and pbs., that might even encourage
more quality medical graduates to enter general practice and enable us to provide good and desperately needed care for our patients, rather than having to turn to practitioners with limited qualifications .


Dr Raymond Weng Yat Yeow   31/08/2024 1:25:21 PM

Question
‘What remains, however, is why there appears to be ample supply for Wegovy, the same ingredient, but the Ozempic supply remains compromised until further notice?

Answer
Wegovy ....1.0 mg cost $260

But Ozempic off label 1.0mg = $150.

So why would the Pharma company sell at $150 when can sell at $260 in a sitaution of global shortage?

Economics 101


Dr Raymond Weng Yat Yeow   31/08/2024 1:44:16 PM

and Wegovy is a wonder medication see
Wegovy Protects Against Deadly COVID Cases
— Non-cardiovascular benefits observed in SELECT trial
30 August 2024
https://www.medpagetoday.com/meetingcoverage/esc/111720