The Freo Street Doctor service is an accredited, mobile, open-access general practice service to improve primary healthcare for people who are homeless and marginalised.

Despite recent exponential growth in research on familial hypercholesterolaemia, there remains a general lack of public and health professional awareness about the disorder.

Screening and management in general practice has the potential for substantial health benefits while requiring relatively modest investments from the health system.

Guidelines on assessing and managing lipid disorders are evolving as new knowledge and treatments emerge to help health professionals and patients decide the best course of disease management.

Primary care has much to offer in the future diagnosis and management of familial hypercholesterolaemia, but it requires greater awareness and a better appreciation of cumulative cholesterol burden.

The recent increased public experience with epidemiological concepts such as contact tracing offers new potential to improve detection and management of familial hypercholesterolaemia.

This paper examines the theory of institutionalisation as applied to individuals entering aged care, providing a framework for GPs to appreciate the processes involved for these individuals.

Patient health literacy is a barrier to both management of familial hypercholesterolaemia and cascade testing.

Recent consensus advice on the care of patients with familial hypercholesterolaemia (FH) supports improved care of patients with FH in the primary care setting.

Street-based general practice services are critical to facilitate easy access to primary and secondary management of chronic multimorbid conditions in marginalised patients.

Familial hypercholesterolaemia, an autosomal dominant genetic condition, affects one in 250 people in Australia. Universal genetic screening of newborns for FH should be provided in Australia.