A woman aged 36 years presented to her general practitioner because of an episode of sudden-onset vertigo, left ear tinnitus, right arm numbness and weakness, difficulty speaking and headache.

Cognitive impairment is common in multiple sclerosis and can have an impact on all aspects of daily life.

Cognitive rehabilitation is person-centred, with interventions chosen in collaboration with the person, based on biopsychosocial case formulation, and with the aim of meeting the person’s goals.

The general practitioner has a vital role in timely diagnosis, effective communication, referral and treatment, which can have a lasting impact on the patient experience.

The identification of hidden illnesses that present with vague symptoms remains an ongoing challenge for all clinicians.

The Focus articles in this month's issue explore a range of endocrine diseases that can be difficult to diagnose due to the oftentimes-vague symptoms.

Diabetic foot ulcers are associated with significant morbidity and mortality and can subsequently lead to hospitalisation and lower limb amputation if not recognised and treated in a timely manner.

There is room for improvement in monitoring patients with early chronic kidney disease when considering alignment with national guidelines.

A man aged 35 years with a 14-pack year history of smoking presented to his general practitioner with a 12-month history of progressive dyspnoea.

Shared medical appointments and programmed shared medical appointments are an innovative approach to chronic disease management.

This article reviews evidence for RASI therapy in patients with advanced CKD, with the aim of enhancing GPs’ awareness to the cardiovascular and renoprotective benefits.

This paper considers common mechanisms underpinning chronic conditions and how these mechanisms might be targeted therapeutically in primary care.

Evidence-informed guideline recommendations on risk treatment thresholds for initiating blood pressure- and lipid-lowering therapy for cardiovascular disease primary prevention is presented.

This study investigates the effectiveness of two interventions to prevent surgical site infection after below-knee surgery.

The unregulated implementation of risk algorithms in tools might miss identifying patients at high risk of cardiovascular disease.