A patient presents with soreness and weakness of both hands, which he developed following the use of a walking frame.

Peripheral neuropathy, peripheral arterial disease and diabetes-related foot ulcers are the most important risk factors for future amputation.

This study tested an innovative intervention to promote physical activity self-management and its impact on foot symptoms.

A greater emphasis on cardiovascular risk factor modification for all patients with peripheral artery disease is required to improve long-term outcomes.

General practitioners should be aware that physical activity might exacerbate symptoms of diabetic peripheral neuropathy when encouraging their patients to be active.

Diabetic foot ulcers are associated with significant morbidity and mortality and can subsequently lead to hospitalisation and lower limb amputation if not recognised and treated in a timely manner.