Medication cessation or dose reduction may be required for patients with chronic kidney disease to prevent medication accumulation, adverse medication events and kidney injury.

Patients with advanced age, significant comorbidities and poor functional status may not gain a survival benefit with dialysis when compared with being managed conservatively.

Buprenorphine–naloxone is well tolerated by patients with chronic pain, and has the potential to improve pain scores and affective symptoms.

Pretreatment assessment and correction of serum calcium and vitamin D levels can reduce the risk of denosumab-related hypocalcaemia in chronic kidney disease.

This paper describes the overall number of prescriptions and unique medicines dispensed and costs borne by a cohort of patients treated with lipid-lowering therapy.

This study assesses the influence of baseline body mass index and baseline knee pain on improvements in patients participating in a weight loss program for knee osteoarthritis.

This article outlines an approach for understanding, explaining and managing chronic pelvic pain in women with a normal laparoscopy.

The aim of this article is to update GPs on how to screen patients for eating disorders across the entire weight spectrum and to diagnose, treat and monitor patients with binge eating disorder.

General practitioners play a crucial part in screening, monitoring and early management of chronic kidney disease mineral and bone disorder (CKD-MBD) in patients with chronic kidney disease.

Cognitive impairment is common in multiple sclerosis and can have an impact on all aspects of daily life.

Cognitive rehabilitation is person-centred, with interventions chosen in collaboration with the person, based on biopsychosocial case formulation, and with the aim of meeting the person’s goals.

Asthma presentations are common in general practice, but opportunities to control asthma are often missed.

Strategies to delay progression of chronic kidney disease include lifestyle advice, prevention of acute kidney injury, control of blood pressure and albuminuria, and disease-specific interventions.

It is reasonable to consider including exercise-based services in the care team to enable patients with non-specific chronic low back pain to transition to self-management.

Many challenges exist in providing best-evidence treatments that promote an active approach facilitating self-efficacy and physical activity, and align with a contemporary understanding of pain.