An overview of the investigation and management of thyroid nodules in general practice.

Increased detection and excellent prognosis of differentiated thyroid cancers has led to a growing cohort of patients undergoing post-treatment survivorship care.

A woman aged 64 years presented with a few weeks of tiredness, night sweats and palpitations.

A woman aged 24 years with no past pregnancies presented with a nine-month history of bilateral nipple discharge and occasional severe headaches during the week after her period.

Rational investigation of thyroid disease requires careful avoidance of over-investigation of minor abnormalities balanced with prompt diagnosis of serious health conditions.

Long-term management requires an understanding of the range of causes and benefits from a shared decision-making approach, with discussion about potential risks and benefits of therapy.

Hypothyroidism requiring T4 replacement is common in pregnancy. Prescribers should be aware that there are no specific concerns about dairy intake with T4.