This review provides a contemporary update on androgen deprivation therapy, with further discussion of emerging novel therapies for primary care.

The advent of new technologies has turned the tide in the diagnosis and treatment of prostate cancer.

There is a need to support men to make informed decisions about prostate-specific antigen testing using appropriate information resources and decision aids.

The relationship between prolonged breast cancer pathways and poorer survival is well established.

Molecular targeting agents are revolutionising treatment options, particularly poly adenosine diphosphate–ribose polymerase inhibitors, especially for patients with an underlying BRCA mutation.

Radiation therapy may be used as definitive treatment for low-risk cancers, as an adjuvant treatment for high-risk disease or alone for inoperable cases.

Prevention and early diagnosis coupled with curative treatments are key strategies for reducing lung cancer mortality by avoiding the sequelae of metastatic disease.

All neck masses should be considered malignant until proven otherwise.

Evidence suggests that exercise has a significant therapeutic effect in the management of cancer.

Exercise testing and prescription for patients with lung cancer adheres to general principles, along with cancer-specific safety considerations.

The management of prostate cancer has changed significantly in recent years, particularly the use of imaging.

Pancreatic cancer has the highest mortality rate among all main cancer types and is the fourth leading cause of cancer death in Australia.

This article focuses on the management of early breast cancer, highlighting recent changes and the role of the general practitioner in supporting women in their decision making and treatment.

When using topical options for treating low-grade lesions, it is important to inform the patient about possible treatment failure and the need to have another intervention if the lesion recurs.

Current evidence for prostate-specific testing to advocate for updating outdated guidelines and resources.