In late-stage Parkinson’s disease there is a shift to increasing disability from non-motor symptoms unresponsive to levodopa.
Imaging algorithms for coronary artery disease screening differ significantly from diagnostic studies evaluating cardiac symptoms including chest pain.
A woman aged 64 years presented with a few weeks of tiredness, night sweats and palpitations.
A woman aged 49 years presented with a 12-month history of an enlarging painless but pruritic perianal plaque 2 cm from the anal verge.
What was once a fatal disease at the severe end of the spectrum is becoming a treatable condition with improved functional status and outcomes.
Our understanding of COVID-19-related renal disease and the effect of the infection in patients with renal disease is still evolving.
International rheumatology bodies now recommend multiple forms of exercise as part of the management of both osteoarthritis and the more classically inflammatory rheumatic disorders.
While it is important to investigate and understand the role of the BCG vaccine in other areas, this should not be at the expense of its proven use for tuberculosis protection.
More than 360 cardiovascular disease risk equations have been developed, many incorporating risk factors not included in the Framingham Risk Equation.
A greater emphasis on cardiovascular risk factor modification for all patients with peripheral artery disease is required to improve long-term outcomes.
Screening with immunological tests is not a proxy for the rational process of formulating a differential diagnosis.
Heart failure with preserved ejection fraction is an emerging global epidemic that requires increased awareness among the primary healthcare community.
An overview of the investigation and management of thyroid nodules in general practice.
Nocturia is associated with significant morbidity and is likely to be a marker of poor health.
Communication difficulties are frequently disregarded until they have a significant impact on quality of life, while the person may be unaware of indicators of dysphagia.